Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus

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Standard

Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus. / Hansen, L; Jensen, J N; Ekstrøm, C T; Vestergaard, H; Hansen, T; Pedersen, O; Vestergaard, Henrik.

I: Diabetologia, Bind 44, Nr. 2, 02.2001, s. 237-240.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hansen, L, Jensen, JN, Ekstrøm, CT, Vestergaard, H, Hansen, T, Pedersen, O & Vestergaard, H 2001, 'Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus', Diabetologia, bind 44, nr. 2, s. 237-240. https://doi.org/10.1007/s001250051605

APA

Hansen, L., Jensen, J. N., Ekstrøm, C. T., Vestergaard, H., Hansen, T., Pedersen, O., & Vestergaard, H. (2001). Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus. Diabetologia, 44(2), 237-240. https://doi.org/10.1007/s001250051605

Vancouver

Hansen L, Jensen JN, Ekstrøm CT, Vestergaard H, Hansen T, Pedersen O o.a. Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus. Diabetologia. 2001 feb.;44(2):237-240. https://doi.org/10.1007/s001250051605

Author

Hansen, L ; Jensen, J N ; Ekstrøm, C T ; Vestergaard, H ; Hansen, T ; Pedersen, O ; Vestergaard, Henrik. / Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus. I: Diabetologia. 2001 ; Bind 44, Nr. 2. s. 237-240.

Bibtex

@article{8d1722b074c311dbbee902004c4f4f50,
title = "Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus",
abstract = "Phosphatase and tensin homologue deleted from chromosome ten (PTEN) has recently been characterized as a novel member in the expanding network of proteins regulating the intracellular effects of insulin. By dephosphorylation of phosphatidyl-inositol-(3, 4, 5)-trisphosphate (PIP3) the PTEN protein regulates the insulin-dependent phosphoinositide 3-kinase (PI3K) signalling cassette and accordingly might function as a regulator of insulin sensitivity in skeletal muscle and adipose tissue. In this study we tested PTEN as a candidate gene for insulin resistance and late-onset Type II (non-insulin-dependent) diabetes mellitus in a Danish Caucasian population.",
keywords = "Adipose Tissue, Adult, Aged, Blood Glucose, Blood Pressure, C-Peptide, Denmark, Diabetes Mellitus, Type 2, European Continental Ancestry Group, Exons, Fasting, Gene Frequency, Humans, Insulin, Insulin Resistance, Middle Aged, Muscle, Skeletal, PTEN Phosphohydrolase, Phosphatidylinositol 3-Kinases, Phosphatidylinositol Phosphates, Phosphoric Monoester Hydrolases, Polymerase Chain Reaction, Polymorphism, Genetic, Polymorphism, Restriction Fragment Length, Polymorphism, Single-Stranded Conformational, Tumor Suppressor Proteins",
author = "L Hansen and Jensen, {J N} and Ekstr{\o}m, {C T} and H Vestergaard and T Hansen and O Pedersen and Henrik Vestergaard",
year = "2001",
month = feb,
doi = "10.1007/s001250051605",
language = "English",
volume = "44",
pages = "237--240",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus

AU - Hansen, L

AU - Jensen, J N

AU - Ekstrøm, C T

AU - Vestergaard, H

AU - Hansen, T

AU - Pedersen, O

AU - Vestergaard, Henrik

PY - 2001/2

Y1 - 2001/2

N2 - Phosphatase and tensin homologue deleted from chromosome ten (PTEN) has recently been characterized as a novel member in the expanding network of proteins regulating the intracellular effects of insulin. By dephosphorylation of phosphatidyl-inositol-(3, 4, 5)-trisphosphate (PIP3) the PTEN protein regulates the insulin-dependent phosphoinositide 3-kinase (PI3K) signalling cassette and accordingly might function as a regulator of insulin sensitivity in skeletal muscle and adipose tissue. In this study we tested PTEN as a candidate gene for insulin resistance and late-onset Type II (non-insulin-dependent) diabetes mellitus in a Danish Caucasian population.

AB - Phosphatase and tensin homologue deleted from chromosome ten (PTEN) has recently been characterized as a novel member in the expanding network of proteins regulating the intracellular effects of insulin. By dephosphorylation of phosphatidyl-inositol-(3, 4, 5)-trisphosphate (PIP3) the PTEN protein regulates the insulin-dependent phosphoinositide 3-kinase (PI3K) signalling cassette and accordingly might function as a regulator of insulin sensitivity in skeletal muscle and adipose tissue. In this study we tested PTEN as a candidate gene for insulin resistance and late-onset Type II (non-insulin-dependent) diabetes mellitus in a Danish Caucasian population.

KW - Adipose Tissue

KW - Adult

KW - Aged

KW - Blood Glucose

KW - Blood Pressure

KW - C-Peptide

KW - Denmark

KW - Diabetes Mellitus, Type 2

KW - European Continental Ancestry Group

KW - Exons

KW - Fasting

KW - Gene Frequency

KW - Humans

KW - Insulin

KW - Insulin Resistance

KW - Middle Aged

KW - Muscle, Skeletal

KW - PTEN Phosphohydrolase

KW - Phosphatidylinositol 3-Kinases

KW - Phosphatidylinositol Phosphates

KW - Phosphoric Monoester Hydrolases

KW - Polymerase Chain Reaction

KW - Polymorphism, Genetic

KW - Polymorphism, Restriction Fragment Length

KW - Polymorphism, Single-Stranded Conformational

KW - Tumor Suppressor Proteins

U2 - 10.1007/s001250051605

DO - 10.1007/s001250051605

M3 - Journal article

C2 - 11270682

VL - 44

SP - 237

EP - 240

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 2

ER -

ID: 96264